Development and characterization of pellets for targeted delivery of 5-fluorouracil and phytic acid for treatment of colon cancer in Wistar rat

Development and characterization of pellets for targeted delivery of 5-fluorouracil and phytic acid for treatment of colon cancer in Wistar rat

The present study was designed to investigate the therapeutic efficacy of metal chelator and anticancer drug in the treatment of colorectal cancer (CRC). Pellets containing Phytic acid, 5- Fluorouracil (5-FU), Microcrystalline cellulose (MCC) PH 101, Hydroxypropyl Methylcellulose (HPMC) and Barium s...

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Bibliographic Details
Main Authors:	Veerpal Kaur, Amit K. Goyal, Goutam Ghosh, Sudam Chandra Si, Goutam Rath
Format:	Article
Language:	English
Published:	Elsevier 2020-01-01
Series:	Heliyon
Subjects:	Materials science Pharmaceutical science Controlled drug delivery 5-flurouracil Phytic acid Colon cancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844019367842

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