Iron deficiency negatively regulates protein methylation via the downregulation of protein arginine methyltransferase

Iron deficiency negatively regulates protein methylation via the downregulation of protein arginine methyltransferase

Iron is an essential trace metal for all biological processes and plays a role in almost every aspect of body growth. Previously, we found that iron-depletion downregulated the expression of proteins, arginine methyltransferase-1 and 3 (PRMT1 and PRMT3), by an iron-specific chelator, deferoxamine (D...

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Bibliographic Details
Main Authors: Hirofumi Inoue, Nobuaki Hanawa, Shin-Ichi Katsumata, Yumi Aizawa, Rie Katsumata-Tsuboi, Miori Tanaka, Nobuyuki Takahashi, Mariko Uehara
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Heliyon
Subjects:
Cell biology
Cell culture
Genetics
Gene expression
Microarray
Biochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020319022

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