Cystic Fibrosis Newborn Screening in Austria Using PAP and the Numeric Product of PAP and IRT Concentrations as Second-Tier Parameters

Cystic Fibrosis Newborn Screening in Austria Using PAP and the Numeric Product of PAP and IRT Concentrations as Second-Tier Parameters

In Austria, newborns have been screened for cystic fibrosis (CF) by analyzing immunoreactive trypsinogen (IRT) from dried blood spots (DBS)s for nearly 20 years. Recently, pancreatitis-associated protein (PAP) analysis was introduced as a second-tier test with the aim of reducing recalls for second...

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Bibliographic Details
Main Authors: Maximilian Zeyda, Andrea Schanzer, Pavel Basek, Vera Bauer, Ernst Eber, Helmut Ellemunter, Margit Kallinger, Josef Riedler, Christina Thir, Franz Wadlegger, Angela Zacharasiewicz, Sabine Renner
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Diagnostics
Subjects:
neonatal screening
recalls
false-positives
IRT×PAP
IRT-PAP
Online Access:https://www.mdpi.com/2075-4418/11/2/299

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