Synthesis and Physicochemical Characterization of Novel Dicyclopropyl-Thiazole Compounds as Nontoxic and Promising Antifungals

Synthesis and Physicochemical Characterization of Novel Dicyclopropyl-Thiazole Compounds as Nontoxic and Promising Antifungals

There is a need to search for new antifungals, especially for the treatment of the invasive <i>Candida</i> infections, caused mainly by <i>C. albicans</i>. These infections are steadily increasing at an alarming rate, mostly among immunocompromised patients. The newly synthes...

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Bibliographic Details
Main Authors: Anna Biernasiuk, Anna Banasiewicz, Maciej Masłyk, Aleksandra Martyna, Monika Janeczko, Angelika Baranowska-Łączkowska, Anna Malm, Krzysztof Z. Łączkowski
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Materials
Subjects:
antifungal activity
<i>Candida albicans</i>
antibiofilm effect
mode of action
cytotoxicity
haemolytic assay
Online Access:https://www.mdpi.com/1996-1944/14/13/3500

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