Molecular Genetic Abnormalities in the Pathogenesis of Hematologic Malignancies and Corresponding Changes in Cell Signaling Systems

Molecular Genetic Abnormalities in the Pathogenesis of Hematologic Malignancies and Corresponding Changes in Cell Signaling Systems

Hematological disorders include a wide spectrum of malignancies of hematopoietic and lymphoid tissues. The genetic changes underlying the pathogenesis of the diseases are specific for each disease. High incidence of chromosomal aberrations (deletion, translocation, insertion) is one of the principal...

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Main Authors: LR Tilova, AV Savinkova, EM Zhidkova, OI Borisova, TI Fetisov, KA Kuzin, OA Vlasova, AS Antipova, OYu Baranova, KI Kirsanov, GA Belitskii, MG Yakubovskaya, EA Lesovaya,5
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2017-04-01
Series:Kliničeskaâ onkogematologiâ
Subjects:
tumors of hematopoietic and lymphoid tissues
chromosomal abnormalities
cell signaling disruption
WHO classification
Online Access:http://bloodjournal.ru/wp-content/uploads/2017/03/13.pdf

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