hHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure.
After severe myocardial infarction (MI), heart failure results from ischemia, fibrosis, and remodeling. A promising therapy to enhance cardiac function and induce therapeutic angiogenesis via a paracrine mechanism in MI is myoblast sheet transplantation. We hypothesized that in a rat model of MI-ind...
Main Authors: | Antti Siltanen, Katsukiyo Kitabayashi, Päivi Lakkisto, Johanna Mäkelä, Tommi Pätilä, Masamichi Ono, Ilkka Tikkanen, Yoshiki Sawa, Esko Kankuri, Ari Harjula |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-04-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21541335/?tool=EBI |
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