hHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure.

After severe myocardial infarction (MI), heart failure results from ischemia, fibrosis, and remodeling. A promising therapy to enhance cardiac function and induce therapeutic angiogenesis via a paracrine mechanism in MI is myoblast sheet transplantation. We hypothesized that in a rat model of MI-ind...

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Bibliographic Details
Main Authors: Antti Siltanen, Katsukiyo Kitabayashi, Päivi Lakkisto, Johanna Mäkelä, Tommi Pätilä, Masamichi Ono, Ilkka Tikkanen, Yoshiki Sawa, Esko Kankuri, Ari Harjula
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21541335/?tool=EBI