Vaccine-Induced CD8+ T Cell Responses in Children: A Review of Age-Specific Molecular Determinants Contributing to Antigen Cross-Presentation

Infections are most common and most severe at the extremes of age, the young and the elderly. Vaccination can be a key approach to enhance immunogenicity and protection against pathogens in these vulnerable populations, who have a functionally distinct immune system compared to other age groups. Mor...

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Bibliographic Details
Main Authors: Elisabeth M. S. Beijnen, Simon D. van Haren
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
CD8
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.607977/full