The Role of Nrf2 Activity in Cancer Development and Progression

The Role of Nrf2 Activity in Cancer Development and Progression

Nrf2 is a transcription factor that stimulates the expression of genes which have antioxidant response element-like sequences in their promoter. Nrf2 is a cellular protector, and this principle applies to both normal cells and malignant cells. While healthy cells are protected from DNA damage induce...

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Bibliographic Details
Main Authors:	Alina-Andreea Zimta, Diana Cenariu, Alexandru Irimie, Lorand Magdo, Seyed Mohammad Nabavi, Atanas G. Atanasov, Ioana Berindan-Neagoe
Format:	Article
Language:	English
Published:	MDPI AG 2019-11-01
Series:	Cancers
Subjects:	nrf2 keap1 signaling pathway oxidative stress cancer targeted genes
Online Access:	https://www.mdpi.com/2072-6694/11/11/1755

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