Identification and Characterization of a Novel IL-4 Receptor α Chain (IL-4Rα) Antagonist to Inhibit IL-4 Signalling

Identification and Characterization of a Novel IL-4 Receptor α Chain (IL-4Rα) Antagonist to Inhibit IL-4 Signalling

Background/Aims: In recent times, allergy has become a financial, physical and psychological burden to the society as a whole. In allergic cascades, cytokine IL-4 binds to IL-4 receptor (IL-4R), consequently producing allergen-specific IgE antibodies by B cells. In addition, among other functions, I...

Full description

Bibliographic Details
Main Authors: Nayyar Ahmed, Pathum Dhanapala, Cenk Suphioglu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Allergy
Phage display
IL-4 signalling pathway
IL-4 receptor
IgE
ELISA
HEK-Blue cell line
Online Access:http://www.karger.com/Article/FullText/430259

Similar Items

Similar Items