Modeling the process of human tumorigenesis

A better understanding of the earliest stages of human cancer formation can enable future improvements in early detection, diagnosis and treatment. In this review, the authors summarize the methods enablingde novotumorigenesis protocols to be applied to human cells and the insights derived from them...

Full description

Bibliographic Details
Main Authors: Sneha Balani, Long V. Nguyen, Connie J. Eaves
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15422
id doaj-0c37a9958528442f9a879a02edc257c5
record_format Article
spelling doaj-0c37a9958528442f9a879a02edc257c52021-05-11T07:57:39ZengNature Publishing GroupNature Communications2041-17232017-05-018111010.1038/ncomms15422Modeling the process of human tumorigenesisSneha Balani0Long V. Nguyen1Connie J. Eaves2Terry Fox Laboratory, British Columbia Cancer AgencyTerry Fox Laboratory, British Columbia Cancer AgencyTerry Fox Laboratory, British Columbia Cancer AgencyA better understanding of the earliest stages of human cancer formation can enable future improvements in early detection, diagnosis and treatment. In this review, the authors summarize the methods enablingde novotumorigenesis protocols to be applied to human cells and the insights derived from them to date, as well as the exciting and relevant technical developments anticipated to extend even further the utility of these strategies.https://doi.org/10.1038/ncomms15422
collection DOAJ
language English
format Article
sources DOAJ
author Sneha Balani
Long V. Nguyen
Connie J. Eaves
spellingShingle Sneha Balani
Long V. Nguyen
Connie J. Eaves
Modeling the process of human tumorigenesis
Nature Communications
author_facet Sneha Balani
Long V. Nguyen
Connie J. Eaves
author_sort Sneha Balani
title Modeling the process of human tumorigenesis
title_short Modeling the process of human tumorigenesis
title_full Modeling the process of human tumorigenesis
title_fullStr Modeling the process of human tumorigenesis
title_full_unstemmed Modeling the process of human tumorigenesis
title_sort modeling the process of human tumorigenesis
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-05-01
description A better understanding of the earliest stages of human cancer formation can enable future improvements in early detection, diagnosis and treatment. In this review, the authors summarize the methods enablingde novotumorigenesis protocols to be applied to human cells and the insights derived from them to date, as well as the exciting and relevant technical developments anticipated to extend even further the utility of these strategies.
url https://doi.org/10.1038/ncomms15422
work_keys_str_mv AT snehabalani modelingtheprocessofhumantumorigenesis
AT longvnguyen modelingtheprocessofhumantumorigenesis
AT conniejeaves modelingtheprocessofhumantumorigenesis
_version_ 1724163737128009728