Suppression of T cells by mesenchymal and cardiac progenitor cells is partly mediated via extracellular vesicles

Suppression of T cells by mesenchymal and cardiac progenitor cells is partly mediated via extracellular vesicles

Adverse remodeling after myocardial infarction (MI) is strongly influenced by T cells. Stem cell therapy after MI, using mesenchymal stem cells (MSC) or cardiomyocyte progenitor cells (CMPC), improved cardiac function, despite low cell retention and limited differentiation. As MSC secrete many facto...

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Bibliographic Details
Main Authors: F. van den Akker, K.R. Vrijsen, J.C. Deddens, J.W. Buikema, M. Mokry, L.W. van Laake, P.A. Doevendans, J.P.G. Sluijter
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Heliyon
Subjects:
Immunology
Stem cell research
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844017339609

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