PFKFB4 Overexpression Facilitates Proliferation by Promoting the G1/S Transition and Is Associated with a Poor Prognosis in Triple-Negative Breast Cancer

PFKFB4 Overexpression Facilitates Proliferation by Promoting the G1/S Transition and Is Associated with a Poor Prognosis in Triple-Negative Breast Cancer

Background. 6-Phosphofructo-2-kinase/fructose-2,6-biphosphate-4 (PFKFB4) is a key factor that plays an important role in tumorigenesis. However, its role in triple-negative breast cancer (TNBC) progression needs to be further validated. We investigated whether PFKFB4 is directly involved in the onco...

Full description

Bibliographic Details
Main Authors: Yu-Chen Cai, Hang Yang, Hong-Bo Shan, Hui-Fang Su, Wen-Qi Jiang, Yan-Xia Shi
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2021/8824589

Similar Items

Similar Items