Helicobacter pylori filtrate impairs spatial learning and memory in rats and increases β-amyloid by enhancing expression of presenilin-2

Helicobacter pylori filtrate impairs spatial learning and memory in rats and increases β-amyloid by enhancing expression of presenilin-2

Helicobacter pylori (H.pylori) infection is related with a high risk of Alzheimer’s Disease (AD), but the intrinsic link between H.pylori infection and AD development is still missing. In the present study, we explored the effect of H.pylori infection on cognitive function and β-amyloid production i...

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Bibliographic Details
Main Authors: Xiu-Lian eWang, Ji eZeng, Jin eFeng, Yi-Tao eTian, Yu-Jian eLiu, Mei eQiu, Xiong eYan, Yang eYang, Yan eXiong, Zhi-Hua eZhang, Qun eWang, Jian-Zhi eWang, Rong eLiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Helicobacter pylori
Learning
Memory
Presenilin-2
Alzheimer's disease
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00066/full

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