Divergent effects of adrenaline in human induced pluripotent stem cell-derived cardiomyocytes obtained from hypertrophic cardiomyopathy

Divergent effects of adrenaline in human induced pluripotent stem cell-derived cardiomyocytes obtained from hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac disease that affects the heart muscle with diverse clinical outcomes. HCM can cause sudden cardiac death (SCD) during or immediately after mild to rigorous physical activity in young patients. However, the mechanism causing SCD as a res...

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Bibliographic Details
Main Authors: Chandra Prajapati, Marisa Ojala, Katriina Aalto-Setälä
Format: Article
Language:English
Published: The Company of Biologists 2018-02-01
Series:Disease Models & Mechanisms
Subjects:
HCM
Arrhythmia
hiPSC-CMs
Adrenaline
Bisoprolol
Online Access:http://dmm.biologists.org/content/11/2/dmm032896

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