Expression of Msx-1 is suppressed in bisphosphonate associated osteonecrosis related jaw tissue-etiopathology considerations respecting jaw developmental biology-related unique features

Expression of Msx-1 is suppressed in bisphosphonate associated osteonecrosis related jaw tissue-etiopathology considerations respecting jaw developmental biology-related unique features

<p>Abstract</p> <p>Background</p> <p>Bone-destructive disease treatments include bisphosphonates and antibodies against the osteoclast differentiator, RANKL (aRANKL); however, osteonecrosis of the jaw (ONJ) is a frequent side-effect. Current models fail to explain the r...

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Bibliographic Details
Main Authors: Schlegel Karl A, Nkenke Emeka, Stockmann Phillip, Ries Jutta, Hyckel Peter, Wehrhan Falk, Neukam Friedrich W, Amann Kerstin
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/96

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http://www.translational-medicine.com/content/8/1/96

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