TmDOTA-tetraglycinate encapsulated liposomes as pH-sensitive LipoCEST agents.

Lanthanide DOTA-tetraglycinate (LnDOTA-(gly)₄⁻) complexes contain four magnetically equivalent amide protons that exchange with protons of bulk water. The rate of this base catalyzed exchange process has been measured using chemical exchange saturation transfer (CEST) NMR techniques as a function of...

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Bibliographic Details
Main Authors: Ana Christina L Opina, Ketan B Ghaghada, Piyu Zhao, Garry Kiefer, Ananth Annapragada, A Dean Sherry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3225356?pdf=render