A New Tetrahydrofuran Lignan Diglycoside from Viola tianshanica Maxim

A new lignan glycoside, tianshanoside A (1), together with a known phenylpropanoid glycoside, syringin (2) and two known lignan glycosides, picraquassioside C (3), and aketrilignoside B (4), were isolated from the whole plant of Viola tianshanica Maxim. The structure of the new compound was elucidat...

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Bibliographic Details
Main Authors: Yan Qin, Chengle Yin, Zhihong Cheng
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/11/13636
Description
Summary:A new lignan glycoside, tianshanoside A (1), together with a known phenylpropanoid glycoside, syringin (2) and two known lignan glycosides, picraquassioside C (3), and aketrilignoside B (4), were isolated from the whole plant of Viola tianshanica Maxim. The structure of the new compound was elucidated by extensive NMR (1H, 13C, COSY, HSQC, HMBC and ROESY) and high resolution mass spectrometry analysis. The three lignans 1, 3, and 4 did not exhibit significant cytotoxicity against human gastric cancer Ags cells or HepG2 liver cancer cells. This is the first report of the isolation of a lignan skeleton from the genus Viola L.
ISSN:1420-3049