Posaconazole Induced Diffuse Lentigines: A Case Report

• Main Authors: Kittipoom Chinhiran, M.D., Charussri Leeyaphan, M.D.
• Format: Article
• Language: English
• Published: Mahidol University 2018-03-01
• Series: Siriraj Medical Journal
• Subjects: Drugs induces multiple lentigines; eruptive lentiginosis; (Siriraj Med J 2018;70: 182-183)
• Online Access: http://www.smj.si.mahidol.ac.th/sirirajmedj/index.php/smj/article/view/2543/2559

Objective: To report a case of posaconazole induced diffuse lentigines. Case presentation: A 57-year-old Thai male with acute promyelocytic leukemia who received chemotherapy and antifungal drug prophylaxis then appeared abruptly generalized multiple discrete well-defined brownish macules on face, lips, trunk, back, both arms, forearms, both thighs, legs, both palms and soles about eight days after received posaconazole. Conclusion: Multiple lentigines could be found in patients who received immunosuppression or immunomodulation, and antifungal drugs such as voriconazole.