Astrocytes and Glutamate Homoeostasis in Alzheimer's Disease: A Decrease in Glutamine Synthetase, But Not in Glutamate Transporter-1, in the Prefrontal Cortex

Astrocytes control tissue equilibrium and hence define the homoeostasis and function of the CNS (central nervous system). Being principal homoeostatic cells, astroglia are fundamental for various forms of neuropathology, including AD (Alzheimer's disease). AD is a progressive neurodegenerative...

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Bibliographic Details
Main Authors: Magdalena Kulijewicz-Nawrot, Eva Syková, Alexander Chvátal, Alexei Verkhratsky, José J. Rodríguez
Format: Article
Language:English
Published: SAGE Publishing 2013-09-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20130017