Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain
<p>Abstract</p> <p>Background</p> <p>Descending facilitation, from the brainstem, promotes spinal neuronal hyperexcitability and behavioural hypersensitivity in many chronic pain states. We have previously demonstrated enhanced descending facilitation onto dorsal horn n...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2009-08-01
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| Series: | Molecular Pain |
| Online Access: | http://www.molecularpain.com/content/5/1/45 |