Regions of homozygosity in the porcine genome: consequence of demography and the recombination landscape.
Inbreeding has long been recognized as a primary cause of fitness reduction in both wild and domesticated populations. Consanguineous matings cause inheritance of haplotypes that are identical by descent (IBD) and result in homozygous stretches along the genome of the offspring. Size and position of...
Main Authors: | Mirte Bosse, Hendrik-Jan Megens, Ole Madsen, Yogesh Paudel, Laurent A F Frantz, Lawrence B Schook, Richard P M A Crooijmans, Martien A M Groenen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3510040?pdf=render |
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