The Putative Metal Coordination Motif in the Endonuclease Domain of Human Parvovirus B19 NS1 Is Critical for NS1 Induced S Phase Arrest and DNA Damage
<p>The non-structural proteins (NS) of the parvovirus family are highly conserved multi-functional molecules that have been extensively characterized and shown to be integral to viral replication. Along with NTP-dependent helicase activity, these proteins carry within their sequences domains t...
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Format: | Article |
Language: | English |
Published: |
Ivyspring International Publisher
2012-01-01
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Series: | International Journal of Biological Sciences |
Online Access: | http://www.biolsci.org/v08p0079.htm |