Circadian oscillations of cytosine modification in humans contribute to epigenetic variability, aging, and complex disease

Circadian oscillations of cytosine modification in humans contribute to epigenetic variability, aging, and complex disease

Abstract Background Maintenance of physiological circadian rhythm plays a crucial role in human health. Numerous studies have shown that disruption of circadian rhythm may increase risk for malignant, psychiatric, metabolic, and other diseases. Results Extending our recent findings of oscillating cy...

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Bibliographic Details
Main Authors: Gabriel Oh, Karolis Koncevičius, Sasha Ebrahimi, Matthew Carlucci, Daniel Erik Groot, Akhil Nair, Aiping Zhang, Algimantas Kriščiūnas, Edward S. Oh, Viviane Labrie, Albert H. C. Wong, Juozas Gordevičius, Peixin Jia, Miki Susic, Art Petronis
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Genome Biology
Subjects:
Epigenetics
DNA modification
Methylation
Circadian
Differentiation
Aging
Online Access:http://link.springer.com/article/10.1186/s13059-018-1608-9

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