The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy

The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy

The mitochondria-targeted antioxidant SkQ1 is a novel drug thought to retard development of age-related diseases. It has been shown that SkQ1 reduces clinical signs of retinopathy in senescence-accelerated OXYS rats, which are a known animal model of human age-related macular degeneration (AMD). The...

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Bibliographic Details
Main Authors:	M. L. Perepechaeva, A. Yu. Grishanova, E. A. Rudnitskaya, N. G. Kolosova
Format:	Article
Language:	English
Published:	Hindawi Limited 2014-01-01
Series:	Journal of Ophthalmology
Online Access:	http://dx.doi.org/10.1155/2014/530943

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