| Summary: | Isolated right ventricle (RV) hypertrophy, anomalous muscle bundles, heavy trabeculations, a redundant hypertrophic papillary muscle, and variations in the shape and thickness of the moderator band (MB), with or without RV hypertrophy, may be confused with a cardiac mass on echocardiography. Therefore, multiple off-axis echocardiographic images and further cross-sectional imaging with cardiac magnetic resonance or computed tomography coronary angiography (CTCA) must be considered in order to avoid unnecessary surgery. We present a case of 65-year-old man with atypical chest pain was referred to our facility for CTCA to evaluate RV mass that was seen on echocardiography, and to evaluate his coronary arteries before attempting a surgical excision of the mass. The echocardiography showed an RV mass that was causing a minimal inflow obstruction. The CTCA showed nonobstructive coronary artery disease, RV hypertrophy, markedly focal thickening of the MB with multiple thickened trabeculations, and muscle bundles extending from the MB to the free wall of the RV. However, but there was no specific feature to suggest a cardiac tumor. Keywords: Right ventricular mass, Right ventricular hypotrophy, Multimodality cardiac imaging
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