Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes

Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes

Summary: Centrosomes are the major microtubule-organizing centers, consisting of centrioles surrounded by a pericentriolar material (PCM). Centrosomal PCM is spatiotemporally regulated to be minimal during interphase and expands as cells enter mitosis. It is unclear how PCM expansion is initiated at...

Full description

Bibliographic Details
Main Authors: Anand Ramani, Aruljothi Mariappan, Marco Gottardo, Sunit Mandad, Henning Urlaub, Tomer Avidor-Reiss, Maria Riparbelli, Giuliano Callaini, Alain Debec, Regina Feederle, Jay Gopalakrishnan
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718319089

Internet

http://www.sciencedirect.com/science/article/pii/S2211124718319089

Similar Items