Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts.

Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts.

Cell-cycle checkpoints and DNA repair processes protect organisms from potentially lethal mutational damage. Compared to other budding yeasts in the subphylum Saccharomycotina, we noticed that a lineage in the genus Hanseniaspora exhibited very high evolutionary rates, low Guanine-Cytosine (GC) cont...

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Bibliographic Details
Main Authors: Jacob L Steenwyk, Dana A Opulente, Jacek Kominek, Xing-Xing Shen, Xiaofan Zhou, Abigail L Labella, Noah P Bradley, Brandt F Eichman, Neža Čadež, Diego Libkind, Jeremy DeVirgilio, Amanda Beth Hulfachor, Cletus P Kurtzman, Chris Todd Hittinger, Antonis Rokas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000255

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