Extracorporeal Partial Nephrectomy with Orthotopic Autotransplantation under Pharmaco-Cold Ischaemia for Cancer of a Single Kidney: A Case Report

• Main Authors: Tatiana Baitman, Irina Miroshkina, Alexander Gritskevich, Alexander Teplov, Andrey Zotikov, Alexander Kochetov, Valentina Demidova, Andrey Chupin, Yulia Stepanova, Wolfgang Schima, Grigory Karmazanovsky
• Format: Article
• Language: English
• Published: Karger Publishers 2020-09-01
• Series: Case Reports in Oncology
• Subjects: renal cell carcinoma; inferior vena cava tumour thrombosis; tumour of a single kidney; nephron-sparing surgery; contrast-enhanced multiple detector computed tomography
• Online Access: https://www.karger.com/Article/FullText/510404
• ISSN: 1662-6575

Up to 10% of patients with renal cell carcinoma (RCC) have locally advanced disease with venous tumour thrombosis involving the inferior vena cava (IVC). 30–50% of them present with synchronous metastatic disease. Surgical treatment remains the only potentially radical method for patients suffering from RCC and IVC tumour thrombosis without distant metastases. Five-year cancer-specific survival for such patients is 40–60%. The role of surgery in the treatment of RCC is significant, even if only cytoreductive operation is possible. Nephron-sparing surgery (NSS) is reasonably preferable for patients suffering from single kidney RCC, but it is not always radical enough. Extracorporeal approach allows to perform a radical dissection of the tumour in special complicated cases, but it is seldom used because of technical difficulties. We present a case of successful NSS by extracorporeal approach in our modification for RCC with IVC tumour thrombosis.