Astragaloside IV Inhibits the Up-Regulation of Wnt/β-Catenin Signaling in Rats with Unilateral Ureteral Obstruction

Astragaloside IV Inhibits the Up-Regulation of Wnt/β-Catenin Signaling in Rats with Unilateral Ureteral Obstruction

Objective: To investigate the effect of Astragaloside IV (AS-IV) on the regulation of the Wnt/β-catenin signaling pathway in rats with unilateral ureteral obstruction (UUO). Methods: Rat renal interstitial fibrosis models were prepared using unilateral ureteral ligation. Rats were randomly divided i...

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Bibliographic Details
Main Authors: Li Wang, Yang-Feng Chi, Ze-Ting Yuan, Wen-Chao Zhou, Pei-Hao Yin, Xue-Mei Zhang, Wen Peng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
UUO model
Renal interstitial fibrosis
Astragaloside IV
Wnt/β-catenin signaling pathway
Online Access:http://www.karger.com/Article/FullText/358699

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