The use of quantitative analysis and Hansen solubility parameter predictions for the selection of excipients for lipid nanocarriers to be loaded with water soluble and insoluble compounds

The aim of these studies was to determine the miscibility of different API with lipid excipients to predict drug loading and encapsulation properties for the production of solid lipid nanoparticles and nanostructured lipid carriers. Five API exhibiting different physicochemical characteristics, viz....

Full description

Bibliographic Details
Main Authors: Pedzisai A. Makoni, Janeeta Ranchhod, Kasongo WaKasongo, Sandile M. Khamanga, Roderick B. Walker
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420300189