Formononetin Attenuates IL-1β-Induced Apoptosis and NF-κB Activation in INS-1 Cells

Formononetin Attenuates IL-1β-Induced Apoptosis and NF-κB Activation in INS-1 Cells

Several studies suggest that the inflammation plays a role in the pathogenesis of some glucose disorders in adults. Exposure of pancreatic β-cells to cytokines, such as interleukin-1β (IL-1β), is thought to contribute to β-cell apoptosis. One important event triggered by IL-1β is induction of nitric...

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Bibliographic Details
Main Authors: Xiao Han, Zhengqiu Zhu, Dong Wang, Zuoling Xie, Han Yin, Yunxia Zhu, Lu Gao, Yao Wang
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Molecules
Subjects:
<em>INS-1</em>
NF-κB
iNOS
formononetin
apoptosis
Online Access:http://www.mdpi.com/1420-3049/17/9/10052

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