Coupled motions direct electrons along human microsomal P450 Chains.

Protein domain motion is often implicated in biological electron transfer, but the general significance of motion is not clear. Motion has been implicated in the transfer of electrons from human cytochrome P450 reductase (CPR) to all microsomal cytochrome P450s (CYPs). Our hypothesis is that tight c...

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Bibliographic Details
Main Authors: Christopher R Pudney, Basile Khara, Linus O Johannissen, Nigel S Scrutton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3243717?pdf=render