Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes
Palladium-catalyzed base-free addition of aryltriolborates to aldehydes has been developed, leading to a wide range of carbinol derivatives in good to excellent yields. The efficiency of this transformation was demonstrated by compatibility with a wide range of functional groups. The present synthet...
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MDPI AG
2017-09-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/22/9/1580 |
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doaj-0b4da0c114c54fcf9367608367d66beb2020-11-25T00:40:21ZengMDPI AGMolecules1420-30492017-09-01229158010.3390/molecules22091580molecules22091580Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to AldehydesKun Hu0Pengqing Ye1Qianqian Zhen2Xinrong Yao3Tong Xu4Yinlin Shao5Jiuxi Chen6College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaPalladium-catalyzed base-free addition of aryltriolborates to aldehydes has been developed, leading to a wide range of carbinol derivatives in good to excellent yields. The efficiency of this transformation was demonstrated by compatibility with a wide range of functional groups. The present synthetic route to carbinol derivatives could be readily scaled up to gram quantity without difficulty. Thus, this method represents a simple and practical procedure to access carbinol derivatives.https://www.mdpi.com/1420-3049/22/9/1580palladium-catalyzedbase-freecarbinol derivativesaryltriolboratesaldehydes |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Kun Hu Pengqing Ye Qianqian Zhen Xinrong Yao Tong Xu Yinlin Shao Jiuxi Chen |
| spellingShingle |
Kun Hu Pengqing Ye Qianqian Zhen Xinrong Yao Tong Xu Yinlin Shao Jiuxi Chen Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes Molecules palladium-catalyzed base-free carbinol derivatives aryltriolborates aldehydes |
| author_facet |
Kun Hu Pengqing Ye Qianqian Zhen Xinrong Yao Tong Xu Yinlin Shao Jiuxi Chen |
| author_sort |
Kun Hu |
| title |
Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_short |
Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_full |
Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_fullStr |
Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_full_unstemmed |
Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_sort |
efficient approach to carbinol derivatives through palladium-catalyzed base-free addition of aryltriolborates to aldehydes |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2017-09-01 |
| description |
Palladium-catalyzed base-free addition of aryltriolborates to aldehydes has been developed, leading to a wide range of carbinol derivatives in good to excellent yields. The efficiency of this transformation was demonstrated by compatibility with a wide range of functional groups. The present synthetic route to carbinol derivatives could be readily scaled up to gram quantity without difficulty. Thus, this method represents a simple and practical procedure to access carbinol derivatives. |
| topic |
palladium-catalyzed base-free carbinol derivatives aryltriolborates aldehydes |
| url |
https://www.mdpi.com/1420-3049/22/9/1580 |
| work_keys_str_mv |
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