Forced swim test in mice: A common animal model of depression
The Forced Swim Test (FST) is a rodent behavioral paradigm utilized for assessment of potential antidepressant-like medications. In this model the mice are put in a plexiglas tank. The tank is loaded with water and the behavior of the mice to escape the tank is scored. The behavioral parameter scor...
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Bangladesh Pharmacological Society
2015-12-01
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| Series: | Bangladesh Journal of Pharmacology |
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| Online Access: | https://www.banglajol.info/index.php/BJP/article/view/25692 |
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doaj-0b4d6bf224e44335864d2fe05e0555fd2020-11-25T02:34:01ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882015-12-01111Forced swim test in mice: A common animal model of depressionMuhammad Aslam0Department of Basic Medical Sciences, Faculty of Pharmacy, Ziauddin University, Karachi 75600 The Forced Swim Test (FST) is a rodent behavioral paradigm utilized for assessment of potential antidepressant-like medications. In this model the mice are put in a plexiglas tank. The tank is loaded with water and the behavior of the mice to escape the tank is scored. The behavioral parameter scored in this test is called immobility, resembling a behavioral state of misery, as seen in human depression. Video Clip of Methodology: Pre-experiment: 50 sec Full Screen Alternate Experiment: 7 min 12 sec Full Screen Alternate https://www.banglajol.info/index.php/BJP/article/view/25692AntidepressantsDepressionForced swim test |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Muhammad Aslam |
| spellingShingle |
Muhammad Aslam Forced swim test in mice: A common animal model of depression Bangladesh Journal of Pharmacology Antidepressants Depression Forced swim test |
| author_facet |
Muhammad Aslam |
| author_sort |
Muhammad Aslam |
| title |
Forced swim test in mice: A common animal model of depression |
| title_short |
Forced swim test in mice: A common animal model of depression |
| title_full |
Forced swim test in mice: A common animal model of depression |
| title_fullStr |
Forced swim test in mice: A common animal model of depression |
| title_full_unstemmed |
Forced swim test in mice: A common animal model of depression |
| title_sort |
forced swim test in mice: a common animal model of depression |
| publisher |
Bangladesh Pharmacological Society |
| series |
Bangladesh Journal of Pharmacology |
| issn |
1991-0088 |
| publishDate |
2015-12-01 |
| description |
The Forced Swim Test (FST) is a rodent behavioral paradigm utilized for assessment of potential antidepressant-like medications. In this model the mice are put in a plexiglas tank. The tank is loaded with water and the behavior of the mice to escape the tank is scored. The behavioral parameter scored in this test is called immobility, resembling a behavioral state of misery, as seen in human depression.
Video Clip of Methodology:
Pre-experiment: 50 sec Full Screen Alternate
Experiment: 7 min 12 sec Full Screen Alternate
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| topic |
Antidepressants Depression Forced swim test |
| url |
https://www.banglajol.info/index.php/BJP/article/view/25692 |
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AT muhammadaslam forcedswimtestinmiceacommonanimalmodelofdepression |
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