Serum vitamin D levels in Indian patients with retinal venous occlusions
Purpose: To estimate serum vitamin D (25 OH D) level in patients of retinal vein occlusion (RVO) and compare it with age-matched controls. Methods and material: Forty patients above 18 years of age with retinal vein occlusion and forty age-matched controls underwent serum vitamin D (Vit D) level est...
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Wolters Kluwer Medknow Publications
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doaj-0b4b87666edf4c22866d609f4b7d6fdd2021-04-02T21:06:27ZengWolters Kluwer Medknow PublicationsSaudi Journal of Ophthalmology1319-45342017-04-01312767910.1016/j.sjopt.2017.03.005Serum vitamin D levels in Indian patients with retinal venous occlusionsAvadhesh OliD. JoshiPurpose: To estimate serum vitamin D (25 OH D) level in patients of retinal vein occlusion (RVO) and compare it with age-matched controls. Methods and material: Forty patients above 18 years of age with retinal vein occlusion and forty age-matched controls underwent serum vitamin D (Vit D) level estimation using a standard protocol. Student’s t test was used to analyse differences between the mean of two groups. Results: The mean age in RVO and control group was 60.25 and 60.73 years respectively. The mean (±SD) level of vitamin D in RVO patients was 13.68 (±4.58) ng/mL (range 5.5–24.8), and the 95% CI of mean was 12.21–15.14 with SD 4.58 while in control group it was 23.03 (±2.89) ng/ml (range 18.4–30.1) with 95% CI of mean being 22.11–23.96 with SD 2.89 (p value of <0.005). While comparing the level of Vitamin D based on type of occlusion the mean level of Vit D in CRVO patients was 15.36 (SD 5.30) and in BRVO it was 12.77 (SD 3.96) which was statistically not significant (p = 0.08). The odds ratio calculated for RVO cases versus controls was 133.33 which was statistically significant (P < 0.05). Conclusions: There is a paucity of published literature on level of Vit D in RVO. This study shows significantly lower levels of serum vitamin D in Indian patients with retinal vein occlusion as compared to age matched controls. Establishment of this correlation has possible implications for prophylaxis or treatment of RVOs.http://www.sciencedirect.com/science/article/pii/S1319453417300371Vitamin DRetinal vein occlusionCardiovascular disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Avadhesh Oli D. Joshi |
spellingShingle |
Avadhesh Oli D. Joshi Serum vitamin D levels in Indian patients with retinal venous occlusions Saudi Journal of Ophthalmology Vitamin D Retinal vein occlusion Cardiovascular disease |
author_facet |
Avadhesh Oli D. Joshi |
author_sort |
Avadhesh Oli |
title |
Serum vitamin D levels in Indian patients with retinal venous occlusions |
title_short |
Serum vitamin D levels in Indian patients with retinal venous occlusions |
title_full |
Serum vitamin D levels in Indian patients with retinal venous occlusions |
title_fullStr |
Serum vitamin D levels in Indian patients with retinal venous occlusions |
title_full_unstemmed |
Serum vitamin D levels in Indian patients with retinal venous occlusions |
title_sort |
serum vitamin d levels in indian patients with retinal venous occlusions |
publisher |
Wolters Kluwer Medknow Publications |
series |
Saudi Journal of Ophthalmology |
issn |
1319-4534 |
publishDate |
2017-04-01 |
description |
Purpose: To estimate serum vitamin D (25 OH D) level in patients of retinal vein occlusion (RVO) and compare it with age-matched controls.
Methods and material: Forty patients above 18 years of age with retinal vein occlusion and forty age-matched controls underwent serum vitamin D (Vit D) level estimation using a standard protocol. Student’s t test was used to analyse differences between the mean of two groups.
Results: The mean age in RVO and control group was 60.25 and 60.73 years respectively. The mean (±SD) level of vitamin D in RVO patients was 13.68 (±4.58) ng/mL (range 5.5–24.8), and the 95% CI of mean was 12.21–15.14 with SD 4.58 while in control group it was 23.03 (±2.89) ng/ml (range 18.4–30.1) with 95% CI of mean being 22.11–23.96 with SD 2.89 (p value of <0.005). While comparing the level of Vitamin D based on type of occlusion the mean level of Vit D in CRVO patients was 15.36 (SD 5.30) and in BRVO it was 12.77 (SD 3.96) which was statistically not significant (p = 0.08). The odds ratio calculated for RVO cases versus controls was 133.33 which was statistically significant (P < 0.05).
Conclusions: There is a paucity of published literature on level of Vit D in RVO. This study shows significantly lower levels of serum vitamin D in Indian patients with retinal vein occlusion as compared to age matched controls. Establishment of this correlation has possible implications for prophylaxis or treatment of RVOs. |
topic |
Vitamin D Retinal vein occlusion Cardiovascular disease |
url |
http://www.sciencedirect.com/science/article/pii/S1319453417300371 |
work_keys_str_mv |
AT avadhesholi serumvitamindlevelsinindianpatientswithretinalvenousocclusions AT djoshi serumvitamindlevelsinindianpatientswithretinalvenousocclusions |
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