Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade

Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade

<p>Abstract</p> <p>The inhibitory receptor programmed death-1 (PD-1) and its ligand, programmed death-ligand 1 (PD-L1) are involved in immune evasion mechanisms for several pathogens causing chronic infections. Blockade of the PD-1/PD-L1 pathway restores anti-virus immune responses...

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Bibliographic Details
Main Authors: Ikebuchi Ryoyo, Konnai Satoru, Shirai Tatsuya, Sunden Yuji, Murata Shiro, Onuma Misao, Ohashi Kazuhiko
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Veterinary Research
Online Access:http://www.veterinaryresearch.org/content/42/1/103

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