Krüppel-like factor 5 is essential for proliferation and survival of mouse intestinal epithelial stem cells

Krüppel-like factor 5 is essential for proliferation and survival of mouse intestinal epithelial stem cells

Krüppel-like factor 5 (KLF5) is a pro-proliferative transcription factor that is expressed in dividing epithelial cells of the intestinal crypt. Leucine-rich repeat-containing G-protein coupled receptor 5 (Lgr5) has been identified as a stem cell marker in both small intestinal and colonic epithelia...

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Bibliographic Details
Main Authors:	Mandayam O. Nandan, Amr M. Ghaleb, Agnieszka B. Bialkowska, Vincent W. Yang
Format:	Article
Language:	English
Published:	Elsevier 2015-01-01
Series:	Stem Cell Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506114001184

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