Levosimendan increases brain tissue oxygen levels after cardiopulmonary resuscitation independent of cardiac function and cerebral perfusion
Abstract Prompt reperfusion is important to rescue ischemic tissue; however, the process itself presents a key pathomechanism that contributes to a poor outcome following cardiac arrest. Experimental data have suggested the use of levosimendan to limit ischemia–reperfusion injury by improving cerebr...
Main Authors: | Andreas García-Bardon, Jens Kamuf, Alexander Ziebart, Tanghua Liu, Nadia Krebs, Bastian Dünges, Robert F. Kelm, Svenja Morsbach, Kristin Mohr, Axel Heimann, Erik K. Hartmann, Serge C. Thal |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-93621-x |
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