The ERα coactivator, HER4/4ICD, regulates progesterone receptor expression in normal and malignant breast epithelium

<p>Abstract</p> <p>The HER4 intracellular domain (4ICD) is a potent estrogen receptor (ERα) coactivator with activities in breast cancer and the developing mammary gland that appear to overlap with progesterone receptor (PgR). In fact, 4ICD has recently emerged as an important regu...

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Bibliographic Details
Main Authors: Howard Beatrice A, Rimm David L, Wansbury Olivia, Giltnane Jennifer M, Das Partha M, Rokicki Jerzy, Jones Frank E
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/150