Inhibition of Src Family Kinases Ameliorates LPS-Induced Acute Kidney Injury and Mitochondrial Dysfunction in Mice

Inhibition of Src Family Kinases Ameliorates LPS-Induced Acute Kidney Injury and Mitochondrial Dysfunction in Mice

Acute kidney injury (AKI), a critical syndrome characterized by a rapid decrease of kidney function, is a global health problem. Src family kinases (SFK) are proto-oncogenes that regulate diverse biological functions including mitochondrial function. Since mitochondrial dysfunction plays an importan...

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Bibliographic Details
Main Authors: Eun Seon Pak, Md Jamal Uddin, Hunjoo Ha
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
acute kidney injury
inflammation
mitochondrial biogenesis
oxidative stress
Src family kinases inhibitor
Online Access:https://www.mdpi.com/1422-0067/21/21/8246

Internet

https://www.mdpi.com/1422-0067/21/21/8246

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