Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms14830 |