Role of thyroid hormone-integrin αvβ3-signal and therapeutic strategies in colorectal cancers

Role of thyroid hormone-integrin αvβ3-signal and therapeutic strategies in colorectal cancers

Abstract Thyroid hormone analogues—particularly, l-thyroxine (T4) has been shown to be relevant to the functions of a variety of cancers. Integrin αvβ3 is a plasma membrane structural protein linked to signal transduction pathways that are critical to cancer cell proliferation and metastasis. Thyroi...

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Bibliographic Details
Main Authors:	Yu-Chen S. H. Yang, Po-Jui Ko, Yi-Shin Pan, Hung-Yun Lin, Jacqueline Whang-Peng, Paul J. Davis, Kuan Wang
Format:	Article
Language:	English
Published:	BMC 2021-04-01
Series:	Journal of Biomedical Science
Subjects:	NDAT Colorectal Cancer Integrin αvβ3 Epidermal growth factor receptor Ras mutation
Online Access:	https://doi.org/10.1186/s12929-021-00719-5

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