A case of recurrent Corynebacterium jeikeium endocarditis: Unanswered questions for the treatment of chronic endovascular infections

A 53-year-old woman with end-stage renal impairment on hemodialysis was evaluated for recurrent episodes of Corynebacterium jeikeium bacteremia and endocarditis. Her recurrences occurred despite surgical debridement and extended courses of culture-directed antimicrobial therapy. The clinical course...

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Main Authors: John-Ross D. Clarke, Manal Abdur Rahman, Zane Saul
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:IDCases
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250919301404
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spelling doaj-0b02fc895a4f4e04b8c3513a2d720cf72021-07-02T04:42:00ZengElsevierIDCases2214-25092019-01-0118A case of recurrent Corynebacterium jeikeium endocarditis: Unanswered questions for the treatment of chronic endovascular infectionsJohn-Ross D. Clarke0Manal Abdur Rahman1Zane Saul2Department of Internal Medicine, Bridgeport Hospital, Yale-New Haven Health System, Bridgeport, CT, 06610, USA; Corresponding author at: 267 Grant Street, Bridgeport, CT, 06610, USA.Department of Internal Medicine, Bridgeport Hospital, Yale-New Haven Health System, Bridgeport, CT, 06610, USADepartment of Infectious Diseases, Bridgeport Hospital, Yale-New Haven Health System, Bridgeport, CT, 06610, USAA 53-year-old woman with end-stage renal impairment on hemodialysis was evaluated for recurrent episodes of Corynebacterium jeikeium bacteremia and endocarditis. Her recurrences occurred despite surgical debridement and extended courses of culture-directed antimicrobial therapy. The clinical course was complicated by the requirement of various endovascular prostheses for vascular access. To our knowledge this degree of relapse with guideline medical and surgical therapy is rare and challenges current practice and understanding of this group of infection. Keywords: Corynebacterium jeikeium endocarditis, Infective endocarditis, Recurrent endovascular infectionhttp://www.sciencedirect.com/science/article/pii/S2214250919301404
collection DOAJ
language English
format Article
sources DOAJ
author John-Ross D. Clarke
Manal Abdur Rahman
Zane Saul
spellingShingle John-Ross D. Clarke
Manal Abdur Rahman
Zane Saul
A case of recurrent Corynebacterium jeikeium endocarditis: Unanswered questions for the treatment of chronic endovascular infections
IDCases
author_facet John-Ross D. Clarke
Manal Abdur Rahman
Zane Saul
author_sort John-Ross D. Clarke
title A case of recurrent Corynebacterium jeikeium endocarditis: Unanswered questions for the treatment of chronic endovascular infections
title_short A case of recurrent Corynebacterium jeikeium endocarditis: Unanswered questions for the treatment of chronic endovascular infections
title_full A case of recurrent Corynebacterium jeikeium endocarditis: Unanswered questions for the treatment of chronic endovascular infections
title_fullStr A case of recurrent Corynebacterium jeikeium endocarditis: Unanswered questions for the treatment of chronic endovascular infections
title_full_unstemmed A case of recurrent Corynebacterium jeikeium endocarditis: Unanswered questions for the treatment of chronic endovascular infections
title_sort case of recurrent corynebacterium jeikeium endocarditis: unanswered questions for the treatment of chronic endovascular infections
publisher Elsevier
series IDCases
issn 2214-2509
publishDate 2019-01-01
description A 53-year-old woman with end-stage renal impairment on hemodialysis was evaluated for recurrent episodes of Corynebacterium jeikeium bacteremia and endocarditis. Her recurrences occurred despite surgical debridement and extended courses of culture-directed antimicrobial therapy. The clinical course was complicated by the requirement of various endovascular prostheses for vascular access. To our knowledge this degree of relapse with guideline medical and surgical therapy is rare and challenges current practice and understanding of this group of infection. Keywords: Corynebacterium jeikeium endocarditis, Infective endocarditis, Recurrent endovascular infection
url http://www.sciencedirect.com/science/article/pii/S2214250919301404
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