Interleukin-9 regulates macrophage activation in the progressive multiple sclerosis brain

Interleukin-9 regulates macrophage activation in the progressive multiple sclerosis brain

Abstract Background Multiple sclerosis (MS) is an immune-mediated, chronic inflammatory, and demyelinating disease of the central nervous system (CNS). Several cytokines are thought to be involved in the regulation of MS pathogenesis. We recently identified interleukin (IL)-9 as a cytokine reducing...

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Bibliographic Details
Main Authors: Gloria Donninelli, Inbar Saraf-Sinik, Valentina Mazziotti, Alessia Capone, Maria Grazia Grasso, Luca Battistini, Richard Reynolds, Roberta Magliozzi, Elisabetta Volpe
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Neuroinflammation
Subjects:
Progressive multiple sclerosis
Interleukin-9
Interleukin-9 receptor
Macrophages
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12974-020-01770-z

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