Identification of immunologic and clinical characteristics that predict inflammatory response to C. Novyi-NT bacteriolytic immunotherapy

Identification of immunologic and clinical characteristics that predict inflammatory response to C. Novyi-NT bacteriolytic immunotherapy

Abstract Background Clostridium novyi-NT (CNV-NT), has shown promise as a bacterolytic therapy for solid tumors in mouse models and in dogs with naturally developing neoplasia. Factors that impact the immunologic response to therapy are largely unknown. The goal of this pilot study was to determine...

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Bibliographic Details
Main Authors: Amy E. DeClue, Sandra M. Axiak-Bechtel, Yan Zhang, Saurabh Saha, Linping Zhang, David D. Tung, Jeffrey N. Bryan
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Veterinary Research
Subjects:
Immunology
Cancer
Canine
Immunotherapy
Online Access:http://link.springer.com/article/10.1186/s12917-018-1424-1

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