Kallikrein gene-modified EPCs induce angiogenesis in rats with ischemic hindlimb and correlate with integrin αvβ3 expression.

BACKGROUND: Human tissue kallikrein (hTK) plays an essential role in the physiological and pathological mechanisms of blood vessels. This study aimed to determine whether angiogenesis induced by endothelial progenitor cells (EPCs) transduced with the adenovirus-mediated hTK gene could improve blood...

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Bibliographic Details
Main Authors: Shen Shen Fu, Fu Ji Li, Yuan Yuan Wang, An Bei You, Yi Liang Qie, Xiao Meng, Jian Rui Li, Bao Chuan Li, Yun Zhang, Qing Da Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3760867?pdf=render