QSAR study on the histamine (H3) receptor antagonists using the genetic algorithm: Multi parameter linear regression

A quantitative structure activity relationship (QSAR) model has been produced for predicting antagonist potency of biphenyl derivatives as human histamine (H3) receptors. The molecular structures of the compounds are numerically represented by various kinds of molecular descriptors. The whole dat...

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Bibliographic Details
Main Authors: Adimi Maryam, Salimi Mahmoud, Nekoei Mehdi
Format: Article
Language:English
Published: Serbian Chemical Society 2012-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391100205A.pdf