An analysis of the sequence variability of meningococcal fHbp, NadA and NHBA over a 50-year period in the Netherlands.

An analysis of the sequence variability of meningococcal fHbp, NadA and NHBA over a 50-year period in the Netherlands.

Studies of meningococcal evolution and genetic population structure, including the long-term stability of non-random associations between variants of surface proteins, are essential for vaccine development. We analyzed the sequence variability of factor H-binding protein (fHbp), Neisserial Heparin-B...

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Bibliographic Details
Main Authors: Stefania Bambini, Jurgen Piet, Alessandro Muzzi, Wendy Keijzers, Sara Comandi, Lisa De Tora, Mariagrazia Pizza, Rino Rappuoli, Diederik van de Beek, Arie van der Ende, Maurizio Comanducci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3663754?pdf=render

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