Anion-sensitive regions of L-type CaV1.2 calcium channels expressed in HEK293 cells.

Anion-sensitive regions of L-type CaV1.2 calcium channels expressed in HEK293 cells.

L-type calcium currents (I(Ca)) are influenced by changes in extracellular chloride, but sites of anion effects have not been identified. Our experiments showed that CaV1.2 currents expressed in HEK293 cells are strongly inhibited by replacing extracellular chloride with gluconate or perchlorate. Va...

Full description

Bibliographic Details
Main Authors: Norbert Babai, Nataly Kanevsky, Nathan Dascal, George J Rozanski, Dhirendra P Singh, Nigar Fatma, Wallace B Thoreson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2798859?pdf=render

Internet

http://europepmc.org/articles/PMC2798859?pdf=render

Similar Items